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[目的]探讨乳腺癌骨转移患者骨显像的特点、规律及临床应用价值。[方法]210例乳腺癌患者静脉注射99mTc-MDP 740～925 MBq后行SPECT全身骨显像。[结果]210例乳腺癌患者中有135例骨骼显像异常,结合临床诊断为乳腺癌骨转移瘤,骨转移发生率为64.3%。年龄≤40岁乳腺癌患者骨转移发生率45.4%,年龄>40岁的乳腺癌患者骨转移发生率为67.8%,差异有统计学意义(P<0.05)。多发病灶119例(88.1%),单发病灶16例(11.9%)。骨转移的部位以肋骨、胸骨为多见,依次为脊柱、骨盆、颅骨等其他骨骼。[结论]核素全身骨显像可早期诊断乳腺癌骨转移,对于临床诊断分期和制定治疗方案具有重要的指导意义。
[Objective] To investigate the characteristics, regularity and clinical value of bone imaging in patients with bone metastasis of breast cancer. [Method] 210 cases of breast cancer patients underwent intravenous injection of 99mTc-MDP 740 ~ 925 MBq SPECT whole body bone imaging. [Results] There were 135 cases of skeletal imaging abnormalities in 210 cases of breast cancer. Combined with clinical diagnosis of bone metastases of breast cancer, the incidence of bone metastasis was 64.3%. The incidence of bone metastasis was 45.4% in patients with breast cancer ≤40 years old and 67.8% in patients with breast cancer> 40 years old (P <0.05). 119 cases of multiple lesions (88.1%), single lesions in 16 cases (11.9%). Bone metastasis to the ribs, sternum is more common, followed by the spine, pelvis, skull and other bones. [Conclusion] Radionuclide bone scintigraphy can early diagnose bone metastasis of breast cancer, which has important guiding significance for clinical staging and treatment planning.