目的评价Loop抗返流双J管对宫颈癌放疗合并梗阻性肾病的临床治疗效果。方法收集本院2008年6月至2014年6月就诊的28例宫颈癌放疗合并梗阻性肾病患者,其中13例患者采用Loop抗返流双J管置入治疗、15例采用普通双J管置入治疗,定期复查尿常规、肾功能及B超,抗返流双J管留置1年,普通双J管每3月更替1次,随访1年,比较2组梗阻性肾病的缓解率、上尿路感染发生率、相关并发症发生率和满意度。结果所有患者随访时间均满1年,与置管前比较,2组患者肾积水程度均明显减轻,术后肾功能水平明显改善,差异无统计学意义(P>0.05)。Loop抗返流双J管组和普通双J管组1年内上尿路感染发生率、相关并发症发生率、满意度分别为7.7%和26.7%、15.4%和53.3%、84.6%和66.7%,差异均有统计学意义(P<0.05)。结论 Loop抗返流双J管对宫颈癌放疗合并梗阻性肾病的治疗效果确切,同时减少上尿路感染,相关并发症发生率低、满意度高,值得在临床推广。 Objective To evaluate the clinical effect of Loop anti-reflux double J tube on cervical cancer radiotherapy combined with obstructive nephropathy. Methods 28 patients with cervical cancer treated with radiotherapy combined with obstructive nephropathy were treated in our hospital from June 2008 to June 2014. Thirteen patients were treated with Loop anti-reflux dual J-tube and 15 patients were treated with common double J-tube Routine urinary routine examination, renal function and B ultrasound, anti-reflux double J tube indwelling for 1 year, ordinary double J tube every 1 month, 1 year follow-up, compared two groups of obstructive nephropathy remission rate, The incidence of urinary tract infection, the incidence of related complications and satisfaction. Results All patients were followed up for 1 year. Compared with those before catheterization, the degree of hydronephrosis in both groups were significantly reduced, and the postoperative renal function improved significantly. There was no significant difference (P> 0.05). The incidence of upper urinary tract infection and the incidence of related complications in the double anti-reflux J and double J groups were 7.7% and 26.7%, 15.4% and 53.3%, 84.6% and 66.7% , The differences were statistically significant (P <0.05). Conclusions Loop anti-reflux double J tube is effective in treating cervical cancer with radiotherapy combined with obstructive nephropathy, reducing upper urinary tract infection, low incidence of complications and high satisfaction, which is worthy of clinical promotion.