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低血钾和高血糖都是噻嗪类利尿药用于治疗高血压时常见的副作用。本文研究了可交换钾或血清钾与治疗剂量的双氢克尿塞引起的空腹血糖升高之间的关系,及补钾对噻嗪类引起的高血糖的影响。材料和方法:24位患高血压的妇女参加了研究(年龄是31—60岁)。研究分两阶段进行:第一阶段(前6—11周),给口服双氢克尿塞,每次50毫克,上、下午8点钟各服药一次;第二阶段(后6周),除维持同剂量的双
Hypokalemia and hyperglycemia are common side effects of thiazide diuretics in the treatment of hypertension. This article examines the relationship between exchangeable potassium or serum potassium and the therapeutic dose of hydrochlorothiazide-induced fasting glucose and the effect of potassium supplementation on thiazide-induced hyperglycemia. MATERIALS AND METHODS: Twenty-four women with hypertension were enrolled (age 31-60 years). The study was divided into two phases: the first phase (6-11 weeks before), to oral hydrochlorothiazide, each 50 mg, on the 8 o’clock, each medication; the second phase (after 6 weeks), in addition to maintaining the same dose double