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在急性冠脉综合征的病理生理学中,全身或局部炎症增加是一个关键因素.现将讨论血液学指标的作用:白细胞、中性粒细胞与淋巴细胞比、红细胞分布宽度和血小板指标(血小板与淋巴细胞比、平均血小板体积与血小板分布宽度).近年来,人们对这些指标产生了浓厚的兴趣,因为它们可能对急性冠脉综合征提供病理生理学、风险分层和预防方面的独立信息,并且检测简便、经济、客观等优势在日常临床实践中非常受欢迎.此外,许多研究指出,在急性心肌梗死、不稳定型心绞痛等疾病发生不良心血管事件、支架内血栓形成、心律失常、再灌注后心肌损伤,甚至死亡等方面都有有效的预后价值.最近的研究也强调,它们在综合分析中与其他标志物结合,使用价值更显著,如肌钙蛋白、全球急性冠状动脉事件注册系统、采用紫杉类药物释放支架的经皮冠脉介入术与心脏外科手术之间的协同作用及心肌梗死溶栓治疗危险评分,提高了急性冠脉综合征患者的风险分层和诊断.“,”An increased systemic or local inflammation plays a key role in the pathophysiology of acute coronary syndrome ( ACS). This review will discuss the role of hematological indices :white blood cells,neutrophil to lymphocyte ratio,red cell distribution width,and platelet indices.This includes;platelet to lymphocyte ratio,mean platelet volume,and platelet distribution width in the case of ACS.In recent years,a strong interest has been drawn to these indices , given that they may provide independent information on pathophysiology , risk stratification,and optimal management.Their low-cost and consequent wide and easy availability have made them very popular in daily clinical practice.Furthermore,many studies have pointed at their effective prognostic value in mortality ,major cardiovascular events ,stent thrombosis,arrhythmias,and myocardial perfusion disorders in terms of acute myocardial infarction and unstable angina .The most recent research also emphasizes their significant value in the combined analysis with other markers ,such as troponin,or with GRACE,SYNTAX,and TIMI scores,which improve risk stratification and diagnosis in ACS patients.