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为了解母婴血清微量元素及免疫球蛋白之间的相互关系,本文测定了104对健康母婴血清铁、铜、锌及免疫球蛋白的含量。结果显示:62例男婴和42例女婴其母血血清铁显著低于新生儿脐血血清铁(P<0.001);男婴母亲血清锌显著低于新生儿脐血血清锌(P<0.001);而女婴母亲血清锌则略低于新生儿脐血血清锌(P>0.5);男女婴其母亲血清铜显著高于新生儿脐血血清铜(P<0.001);男女婴其母亲血清IgG明显低于新生儿脐血血清IgG(P<0.001)。母亲血清铁、锌、IgG与新生儿脐血血清铁,锌、IgG相关分析呈正相关,而母亲血清铜与新生儿脐血血清铜则呈负相关。104例新生儿脐血血清IgG与自身血清铁、铜、锌呈负相关。提示:孕期除全面加强营养外需要另外补充富合微量元素的食物;血清铁、铜、锌与机体免疫系统有一定的关系,但不能仅仅依靠IgG的量来衡量,而应进一步作IgG亚类及T、B细胞功能的检查。
In order to understand the relationship between maternal serum trace elements and immunoglobulin, the content of iron, copper, zinc and immunoglobulin in 104 healthy maternal and infant serum was determined in this paper. The results showed that the serum iron of maternal blood of 62 male and 42 female infants was significantly lower than that of neonatal umbilical serum (P <0.001). The maternal serum zinc of maternal infants was significantly lower than that of newborns <0.001). Serum zinc of the mother’s baby was slightly lower than that of the umbilical serum (P> 0.5). The serum copper of her mother’s baby was significantly higher than that of the newborn’s umbilical serum (P <0. 001). The serum IgG levels of mothers in both boys and girls were significantly lower than those in neonates (P <0.001). Serum levels of iron, zinc and IgG in maternal mothers were positively correlated with iron, zinc and serum IgG levels in cord blood of neonates, but negatively correlated with copper levels in maternal serum and neonatal cord blood serum. Serum IgG in 104 newborns was negatively correlated with serum iron, copper and zinc. Tip: In addition to comprehensive nutrition during pregnancy need additional supplementation of trace amounts of trace elements in food; serum iron, copper, zinc and immune system have a certain relationship, but can not rely solely on the amount of IgG to measure, but should be further for IgG subclasses and T, B cell function check.