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目的:研究影响细辛在复方中功效发挥方向的因素(配伍、剂量、剂型、用法),以便于可以更好地控制方剂药效发挥的方向。方法:在《中医方剂大辞典》中搜集913副含有细辛的方剂,利用数据库应用数据资料总结归纳的方式统计细辛在复方中功效发挥方向的影响因素。结果:方剂中常与细辛配伍使用的药类有化痰止咳平喘药、解表药、补虚药、温里药、清热药以及活血化瘀药。细辛常见的配伍结构有细辛配麻黄,细辛配荆芥,细辛配防风等。细辛小剂量常用于解表、通窍、通阳,多选用汤剂与煮散,中量化饮多选汤剂,大量止痛多用散剂内服或外用。结论:影响细辛功效方向的是多个因素综合控制的,最主要的因素还是配伍。
OBJECTIVE: To study the factors (compatibility, dosage, dosage form and usage) that affect the direction of Asarum in the compound efficacy in order to better control the direction of prescription efficacy. Methods: A total of 913 prescriptions containing Asarum were collected from the Dictionary of Chinese Medicine Prescriptions, and the influencing factors on the direction of the efficacy of Asarum in compound prescriptions were analyzed by using the data summarized in the database. Results: Prescriptions often used in combination with Asarum drugs Huatan Zhike asthma drugs, relieving drugs, tonic drugs, temperature medicine, heat medicine and blood circulation drugs. Asarum common compatibility structure Asarum with ephedra, Asarum with Nepeta, Asarum with wind and so on. Asarum small dose commonly used in the solution table, Tongqiao, Tong Yang, and more soup and boiled powder, decoction more decoction, a large number of painkillers and oral or external use. Conclusion: The direction of Asarum efficacy is controlled by a number of factors, the most important factor is compatibility.