论文部分内容阅读
目的探讨Survivin基因在食管癌变过程中表达的变化。方法应用免疫组化S-P法检测Survivin基因在17例癌变组和40例非癌变组中的表达。结果 Survivin在癌变组中的表达降低(P<0.05)。结论 Survivin基因的表达和食管癌的发生有关,该基因表达的变化可能是食管癌变过程中的早期事件。
Objective To investigate the expression of Survivin gene in esophageal carcinogenesis. Methods The expression of Survivin gene was detected by immunohistochemical S-P method in 17 cancerous and 40 non-cancerous cases. Results The expression of Survivin in the carcinogenesis group was decreased (P <0.05). Conclusion The expression of Survivin gene is related to the occurrence of esophageal cancer. The change of the gene expression may be an early event in the carcinogenesis of esophageal cancer.