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目的 :观察拉米夫定 (Lamivudine)对慢性乙肝的临床疗效.方法 :对 3 2例慢性乙肝患者给予拉米夫定口服 ,连续1年 ,观察其疗效.结果 :服药至 1年时HBeAg转阴率 4 5%,HBVDNA转阴率 89%,ALT复常率 87%.结论 :拉米夫定对慢性乙肝有较好的疗效 ,值得临床推广应用“,”Objective:To observe the clinical effect of Lamivudine treatment in chronic hepatitis B. Methods:32 cases of chronic hepatitis B were abserved in taking Lamivudine orally 150～75mg per day one year or more.Result: After one year\'\'s treatment,the response rate of HBeAg was 45%,HBV DNA response rate was 89%,and the ALT normalization rate was 87%. Conclusion: The effect of Lamivudine on in chronic hepatitis B is fairly good.