促酰基化蛋白是由脂肪组织分泌的一种碱性小分子蛋白,可刺激脂肪组织摄取脂肪酸,增强原位脂蛋白脂酶活性,增加甘油三酯的储存,降低血甘油三酯水平;还可增加葡萄糖的转运,促进脂肪细胞合成甘油三酯。趋化蛋白受体样蛋白是促酰基化蛋白的特异功能性受体。促酰基化蛋白-趋化蛋白受体样蛋白信号通路的失衡可导致肥胖、代谢综合征和高脂血症等多种疾病。 Promote acylated protein is a small alkaline protein secreted by adipose tissue, which can stimulate fat tissue to uptake fatty acids, increase lipoprotein lipase activity in situ, increase triglyceride storage and lower triglyceride levels. Increase glucose transport, promote fat cells to synthesize triglycerides. Chemotactic protein receptor-like proteins are specific functional receptors of acylated proteins. The imbalance of the pro-acylated protein-chemotactic protein receptor-like protein signaling pathway can lead to a variety of diseases such as obesity, metabolic syndrome and hyperlipidemia.