目的 探讨产前超声筛查在乙型肝炎孕妇胎儿检查中的应用.方法 回顾性分析在我院行孕中期胎儿畸形筛查的4 368例乙肝孕妇超声资料.结果 4 368例乙肝孕妇中胎儿畸形46例,超声检出42例,漏诊4例,畸形率约1.05％,超声检出准确率约91.30％.42例胎儿畸形为:心脏畸形12例,泌尿系统畸形12例,颜面部畸形7例,颅脑畸形5例,胎儿长骨发育异常2例,持续右脐静脉2例,胎儿多发畸形2例.乙肝孕妇常见胎儿畸形发生率与文献报道普通孕妇组差异无统计学意义.结论 产前超声筛查能有效检出乙肝孕妇胎儿畸形,畸形率无显著增高,有效降低了畸形儿的出生率,保障了乙肝孕妇母婴的健康.“,”Objective To discuss the application of prenatal ultrasound screening in pregnant women with hepatitis B (HBV).Methods The ultrasonic data of 4368 HBV pregnant women were analyzed retrospective during the mid-term pregnancy in our hospital.Results Fetal malformation 46 fetus with were found in 4368 HBV cases.42 cases were detected by ultrasound and 4 cases missed,the rate of malformation was about 1.05 ％,and the accuracy rate of ultrasonic detection was about 91.30％.Among 42 cases with fetal malformation,12 cases were cardiac malformation,12 cases of urinary system malformation,7 cases of facial deformity,5 cases of craniocerebral malformation,2 cases of fetal long bone dysplasia,2 cases of right umbilical vein and 2 cases of fetal multiple malformation.The incidence of common fetal malformation in HBV pregnant women was not significantly different from that of the literature reported in the common pregnant women.Conclusions Prenatal ultrasound screening can effectively detect fetal malformations in HBV pregnant women,the rate of malformation is not significantly increased.Prenatal ultrasound screening can effectively reduce the birth rate of malformed children and ensure the health of HBV pregnant women and infants.