日本神户消息:广岛大学直木川琦领导的一个小组在日本维生素协会会议上报告,实验性投给维生素E(α-生育酚)可减轻缺血性肝损害。该小组说,维生素E有此作用是由于它能抑制伴随缺血后恢复血流时所产生的造成缺血细胞损害的过氧化脂肪,或者促进三磷酸腺苷重新合成。该小组曾报道过,缺血性肝细胞损害的主要原因是过氧化脂质所导致的生物膜损伤;在缺血前给予辅酶Q,可抑制脂质的过氧化反应。他们还发现,在缺血时,肝组织和线粒体内的 KOBE, Japan: A team led by Naoki Kawaki, Hiroshima University, reported at the Japan Vitamin Association meeting that experimental dosing of vitamin E (alpha-tocopherol) can reduce ischemic liver damage. The team said vitamin E has this effect because it inhibits peroxisomal lipids that cause ischemic damage when resuscitating blood flow after ischemia, or promotes adenosine triphosphate resynthesis. The team reported that the main cause of ischemic hepatocellular damage is biofilm damage caused by lipid peroxidation; coenzyme Q administered before ischemia inhibits lipid peroxidation. They also found that within ischemia and liver tissue and within the mitochondria