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本文研究了56例心衰伴室性心律失常(())病人的疗效。按心衰程度将病人分为两组:第1组25例为Ⅰb期和Ⅱ期心衰,第2组31例为Ⅱb期心衰。两组病人室早的总数相近,但第2组成对室早病人数约为第1组的2倍,室速约为6倍。在2～3周中对每例病人研究了2～3种抗心律失常制剂的疗效:35例用乙吗噻嗪,34例用吡二丙胺,31例用胺碘酮。停止制剂后2～5天恢复心律失常时开始每日服地高辛0.5～0.75 mg,共7天。第2组病人同时加用利尿剂和钾盐,10例加用硝异山梨醇。于治疗的第8～10天用放射免疫法测定血中地高辛浓度。以级数高的室早(成对和/或成簇)的消
This article studied the efficacy of 56 patients with heart failure and ventricular arrhythmia (). According to the degree of heart failure, the patients were divided into two groups: 25 cases of group Ⅰ were stage Ⅰb and Ⅱ heart failure, group 2 of 31 cases of stage Ⅱ b heart failure. The total number of patients in both groups was similar, but the number of patients in group 2 was twice as high as that in group 1 and the ventricular tachycardia was about 6 times. Efficacy of 2 to 3 antiarrhythmic agents was studied in 2 to 3 weeks for each patient: ethmothiazide was used in 35 patients, pyrilamine in 34 patients and amiodarone in 31 patients. 2 to 5 days after stopping the regimen of arrhythmia, daily doses of digoxin 0.5 to 0.75 mg were administered for a total of 7 days. Group 2 patients also added diuretics and potassium salts, 10 cases with additional isosorbide. In the treatment of 8 to 10 days by radioimmunoassay of blood concentrations of digoxin. Room early (paired and / or clustered) elimination in series