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目的：探究腹腔镜与开腹阑尾切除术在急性穿孔性阑尾炎治疗中的疗效。方法选取我院2015年2月～2016年2月收治的80例急性穿孔性阑尾炎患者，按照手术方法的不同将其分为对照组和观察组，各40例，观察组采用腹腔镜阑尾炎切除术进行治疗，对照组采用传统开腹阑尾切除术进行治疗，比较两组患者的临床治疗效果，手术时间，住院时间，术后排气时间和术后并发症发生率。结果观察组的治疗效果优于对照组，手术时间、住院时间和术后排气时间短于对照组，术后并发症发生率低于对照组，两组差异显著（P<0.05），有统计学意义。结论采用腹腔镜阑尾炎切除术治疗急性穿孔性阑尾炎患者具有较大的意义，可较好的提高患者的治疗效果，缩短患者的手术时间、住院时间和术后排气时间，降低患者的术后并发症的发生率，为该病患者的治疗提供较为科学的临床价值。“,”[] objective: to explore the laparoscopic and open appendectomy in efifcacy in the treatment of acute perforated appendicitis. Methods: from February 2015 to February 2015 treated 80 cases of patients with acute perforated appendicitis, according to the operation method of the different divided into control group and observation group, the 40 cases, observation group was treated with laparoscopic resection of appendicitis, the control group treated with traditional open appendectomy, compare clinical therapeutic effects of two groups of patients, operation time, hospital stay, postoperative exhaust time and incidence of postoperative complications. Results: the curative effect of observation group is better than the control group, operation time, length of hospital stay and postoperative exhaust time shorter than the control group, postoperative complication rate is lower than the control group, signiifcant difference was found in two groups (P < 0.05), with statistical signiifcance. Conclusion: the laparoscopic resection in treatment of acute perforated appendicitis appendicitis patients has great signiifcance, can be better to improve the therapeutic effect of patients, shorten the operation time, length of hospital stay and postoperative patients with exhaust time and reduce the incidence of postoperative complications of patients, for the treatment of patients with the disease to provide more scientiifc clinical value.