本实验的目的是观察1000mg/m~3汽油吸入对小鼠肝脏形态学的影响.60只小鼠随机分为两组.结果发现,对照组与实验组肝细胞坏死差异非常明显(P<0.01);门管区炎细胞浸润除每天吸入2小时与对照组无明显差异外,其余随时间延长,差异明显增加.中央静脉及周围肝窦不规则扩张与吸入时间呈反比,即随每天吸入时间延长,扩张数明显减少.这种改变可视为肝脏早期损伤的特征之一. The purpose of this experiment was to observe the effects of inhalation of 1000mg / m3 petrol on liver morphology in mice.All the 60 mice were randomly divided into two groups.The results showed that there was significant difference between the control group and the experimental group (P <0.01) ). The infiltration of inflammatory cells in portal area in addition to the daily intake of 2 hours and the control group no significant difference, the other with time, the difference was significantly increased.Central veins and peripheral sinusoidal irregular expansion and inhalation time is inversely proportional to that with the inhalation time is prolonged , The number of expansion significantly reduced.This change can be regarded as one of the characteristics of early liver injury.