论文部分内容阅读
目的探讨依那普利联合双氢克脲噻治疗老年收缩期高血压患者的疗效及临床分析。方法 2011年1月至2012年1月期间,我院诊治的100例老年收缩期高血压患者,给予依那普利联合双氢克脲噻治疗,治疗6个月后,对治疗前后收缩压和舒张压,以及脉压差的变化情况,进行观察和比较。结果与治疗前相比,治疗后收缩压和舒张压均明显下降,脉压差显著缩小,P<0.05为差异有统计学意义。治疗期间未出现严重的并发症,其中8例出现干咳,1例由于无法忍受,而被迫退出实验,其余7例干咳患者,均在术后3个月内逐渐消失。结论对于老年收缩期高血压患者,依那普利联合双氢克脲噻治疗能够有效控制血压水平,并且降低脉压差,值得临床广泛推广。
Objective To investigate the efficacy and clinical analysis of enalapril combined with hydrochlorothiazide in the treatment of elderly patients with systolic hypertension. Methods From January 2011 to January 2012, 100 elderly hypertensive patients diagnosed and treated in our hospital were given enalapril combined with hydrochlorothiazide. After 6 months of treatment, the systolic pressure and Diastolic pressure, and changes in pulse pressure difference were observed and compared. Results Compared with those before treatment, the systolic and diastolic blood pressures were significantly decreased and the pulse pressure difference was significantly reduced after treatment. P <0.05 was considered as statistically significant. No serious complications occurred during the treatment. Among them, 8 cases developed dry cough, one was forced to withdraw from the experiment due to intolerance, and the remaining 7 cases of dry cough disappeared within 3 months after operation. Conclusion In elderly patients with systolic hypertension, enalaprol combined with hydrochlorothiazide thiazide therapy can effectively control blood pressure, and reduce the pulse pressure difference, it is widely used clinically.