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目的：观察复方丹参注射液用于冠心病非心脏手术术中心肌缺血的治疗。方法：冠心病非心脏手术１０８例，随机分为对照组５４例（术中缺血时用硝酸酯类等药物对症治疗），丹参组５４例（术中加入复方丹参注射液治疗）。术中及术毕观察心电图（ＥＣＧ）、心率（ＨＲ）、平均动脉压（ＭＡＰ）、脉搏血氧饱和度（ＳｐＯ２）、手术失血量，以ＥＣＧ做为疗效评定标准。结果：丹参组总有效率为９０７％，对照组总有效率为３５２％（Ｐ＜００１）。丹参组ＨＲ无明显变化，而对照组ＨＲ增快（Ｐ＜００５）。ＭＡＰ、ＳｐＯ２治疗前后或组间比较无显著差异；失血量两组无明显差异。结论：复方丹参注射液对冠心病非心脏手术术中心肌缺血有明显的改善和保护作用，无明显副作用，是安全有效的措施。
Objective: To observe the treatment of myocardial ischemia caused by non-cardiac surgery for coronary heart disease with compound Danshen injection. Methods: 108 cases of non-cardiac surgery for coronary heart disease were randomly divided into control group (54 cases treated with nitrate and other drugs during ischemia) and 54 cases of Salvia miltiorrhiza group (treated with Danshen injection during operation). Intraoperative and postoperative observation of electrocardiogram (ECG), heart rate (HR), mean arterial pressure (MAP), pulse oxygen saturation (SpO2), surgical blood loss, ECG as the efficacy evaluation criteria. Results: The total effective rate of Danshen group was 90.7%, and the total effective rate of the control group was 35. 2% (P<0. 01). There was no significant change in HR in the Salvia miltiorrhiza group, but it was faster in the control group (P<005). There was no significant difference before and after MAP, SpO2 treatment or between groups; there was no significant difference in blood loss between the two groups. Conclusion: Compound salvia miltiorrhiza injection can obviously improve and protect myocardial ischemia in coronary heart disease non-cardiac surgery. It has no obvious side effect and is a safe and effective measure.