目的 :评价准分子激光角膜切削术 (photorefractivekeratectomy,PRK)治疗高度近视的远期疗效。方法 :将 10 4例 183眼屈光度 >- 6 .0 0D患者分两组 ,Ⅰ组 - 6 .2 5～ - 10 .0 0D ,Ⅱ组≥ - 10 .2 5D ,对PRK术后 3年患者的视力、屈光度、角膜上皮下基质混浊进行随访分析。结果 :3年时Ⅰ组裸眼视力达到术前最佳矫正视力的为 73.3% (96眼 ) ,Ⅱ组为 38.5 % (2 0眼 ) ;屈光度在预期矫正度± 1.0 0D以内者 ,Ⅰ组为 76 .3% (10 0眼 ) ,Ⅱ组为 42 .3% (2 2眼 ) ;角膜上皮下基质混浊 ,3年时 0～ 0 .5级的Ⅰ组为 10 0 % ,Ⅱ组为 90 .4%。结论 :PRK治疗- 6 .2 5～ - 10 .0 0D的高度近视远期疗效较好 ,大于 - 10 .0 0D的远期疗效不理想 Objective: To evaluate the long-term efficacy of photorefractive keratectomy (PRK) in the treatment of high myopia. Methods: A total of 104 patients with 183 eyes of refraction> -60.0D were divided into two groups. Patients in group Ⅰ (-6.52-10.0.0D) and patients in group Ⅱ (≥10.25D) Visual acuity, refraction, corneal submuscular matrix opacity for follow-up analysis. Results: At 3 years, the uncorrected visual acuity of group Ⅰ was 73.3% (96 eyes), and that of group Ⅱ was 38.5% (20 eyes). In group Ⅰ, the corrected visual acuity was within ± 1.0 0D 76.3% (100 eyes), 42.3% (22 eyes) in group Ⅱ, cloudy corneal submucous macules, 100% in group Ⅰ of 0 ~ 0.5 at 3 years and 90% in group Ⅱ .4%. CONCLUSION: The long-term effect of PRK treatment in high myopia from 6.52 to 10.0D is better than that of -10.0D