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对22例LL、28例TT、9例BT、8例BL病人的血清免疫球蛋白IgG、IgA及IgM作了鉴定,并以其与50例正常成年男性作比较。在TT、BT及LL病人中,其IgM虽有不同程度的升高,但与对照组比较时,无显著统计学上的价值。在TT、BL及LL病人中,IgA平均值虽也升高,但在统计学上无意义。与其他类型及对照组相比较,BT病人的IgA则显著降低。LL病人的IgG则显著升高。推测瘤型病人的丙种球蛋白、IgG、IgA及IgM之所以坚定地升高,可能是由于巨噬细胞封闭妨碍了“抑制性T细胞”参与对免疫球蛋白的自身稳定性控制。
Serum immunoglobulin IgG, IgA and IgM of 22 patients with LL, 28 patients with TT, 9 patients with BT, and 8 patients with BL were identified and compared with 50 normal adult men. In patients with TT, BT and LL, although IgM increased to varying degrees, but compared with the control group, no significant statistical value. In patients with TT, BL, and LL, mean increases in IgA were statistically insignificant. Compared with other types and controls, IgA in BT patients was significantly lower. IgG was significantly increased in LL patients. It is speculated that neoplastic immunoglobulins, IgG, IgA, and IgM are strongly elevated in neoplastic patients probably because macrophage closure prevents “suppressive T cells” from participating in the control of self-stability of immunoglobulins.