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本文观察了7例口腔癌经动脉介入栓塞化疗后的病理形态学改变。结果表明经治疗后肿瘤组织明显缩小,溃疡减轻,与正常组织界限清楚;癌瘤组织结构不清,癌细胞明显减少,并出现核固缩、空泡变性和灶状凝固性坏死,癌巢崩解,增生的纤维结缔组织包裹、机化崩解的癌巢,其周围组织大量的炎性细胞浸润;细胞之间的连接结构消失,间隙增宽。术前采用此治疗方法,易于辩别正常组织与瘤体组织之间的界限,有利于保存组织,减少术中出血,减少肿瘤播散与转移的机会,特别是对一些晚期肿瘤以及生长在重要部位的肿瘤,在增加手术机会,提高治愈率方面,有一定的价值。
This article observed seven cases of oral cancer after arterial chemoembolization pathological changes. The results showed that after treatment, tumor tissue was significantly reduced, ulcer reduced, with clear boundaries of normal tissue; tumor tissue structure is unclear, significantly reduced cancer cells, and the nuclear pyknosis, vacuolar degeneration and focal coagulation necrosis, cancer collapse Solution, hyperplastic fibrous connective tissue parcels, mechanical disintegration of cancer nests, the surrounding tissue a large number of inflammatory cell infiltration; the connection between the cell structure disappears, the gap widened. Preoperative use of this treatment method, easy to distinguish between the normal tissue and tumor tissue between the boundaries, is conducive to preservation of tissue, reduce intraoperative bleeding and reduce the spread of cancer and metastasis opportunities, especially for some advanced tumors and growth is important Parts of the tumor, in increasing the chance of surgery, improve the cure rate, there is a certain value.