AIM:To explore the prevalence of amebiasis in inflammatorybowel disease (IBD) in Turkey.METHODS:In this study,amoeba prevalence in 160 casesof IBD,130 of ulcerative colitis and 30 of Crohn’s diseasewere investigated in fresh faeces by means of wetmount+Lugol’s iodine staining,modified formol ethyl acetateand trichrome staining methods and to compare thediagnostic accuracy of wet mount+Lugol’s iodine staining,modified formol ethyl acetate and trichrome staining methodsin the diagnosis of Entamoeba histolytica (E.histolytica)/Entamoeba dispar (E.dispar).RESULTS:E.histolytica/E,dispar cysts and trophozoiteswere found in 14 (8.75 %) of a total of 160 cases,13 (10.0 %)of the 130 patients with ulcerative colitis and 1 (3.3 %) ofthe 30 patients with Crohn’s disease.As for the 105 patientsin the control group who had not any gastrointestinalcomplaints,2 (1.90 %) patients were found to have E.histolytica/E,disparcysts in their faeces.Parasite prevalencein the patient group was determined to be significantly higherthan that in the control group (Fischer’s Exact Test,P<0.05).When the three methods of determining parasites werecompared with one another,the most effective one was foundto be trichrome staining method (KruskaI-Wallis Test,P<0.01).CONCLUSION: Consequently, amoeba infections in IBD cases have a greater prevalence compared to the normal population. The trichrome staining method is more effective for the detection of E. histolytica IE. ofeparthan the wet mount+Lugol’s iodine staining, modified formol ethyl acetate methods. AIM: To explore the prevalence of amebiasis in inflammatory bowel disease (IBD) in Turkey. METHODS: In this study, amoeba prevalence in 160 cases of IBD, 130 of ulcerative colitis and 30 of Crohn’s disease were investigated in fresh faeces by means of wetmount + Lugol’s iodine staining, modified formol ethyl acetate and trichrome staining methods and to compare the diagnostic accuracy of wet mount + Lugol’s iodine staining, modified formol ethyl acetate and trichrome staining methods in the diagnosis of Entamoeba histolytica (E. histolytica) / Entamoeba dispar (E. dispar) .RESULTS : E. histolytica / E, dispar cysts and trophozoites were found in 14 (8.75%) of a total of 160 cases, 13 (10.0%) of the 130 patients with ulcerative colitis and 1 (3.3%) of the 30 patients with Crohn’s disease. As for the 105 patients in the control group who had not any gastrointestinalcomplaints, 2 (1.90%) patients were found to have E. histolytica / E, disparcysts in their faeces. Palasite prevalence in the patient group was determined to be significantly higherthan that in the control group (Fischer’s Exact Test, P <0.05) .When the three methods of determining parasites were compared with one another, the most effective one was found to be trichrome staining method (Kruskal-Wallis Test, P <0.01). CONCLUSION: Causes, amoeba infections in IBD cases have a greater prevalence than to the normal population. The trichrome staining method is more effective for the detection of E. histolytica IE. Ofeparthan the wet mount + Lugol’s iodine staining, modified formol ethyl acetate methods.