骨巨细胞瘤是一种原发性骨肿瘤,约占骨肿瘤的5%,形态学上表现为良性,却具有恶性生物学行为,极少有自愈倾向。骨巨细胞瘤有较强的侵袭性,可穿过骨皮质并形成较大的软组织包块,有少数病例可发生肺转移,肺内转移灶通常生长慢,而肺外转移少见。个别病例可发生局部病灶恶变[1,2],多 Giant cell tumor of bone is a primary bone tumor, accounting for about 5% of bone tumors, morphologically benign, but has a vicious biological behavior, very few tend to heal. Giant cell tumor of bone is more aggressive, can penetrate the cortical bone and the formation of larger soft tissue mass, a small number of cases of lung metastasis may occur, lung metastasis usually grow slowly, and extrapulmonary metastasis rare. Local cases of malignant lesions may occur in some cases [1,2], and more