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目的探讨186例青年人肺癌的临床特点及预后分析。方法选择2001年2月至2011年2月间我院收治的186例青年肺癌患者作为观察组,选择同期住院的180例老年肺癌患者作为对照组。比较两组患者的半年、1年和2年生存期及两组临床特点的差别。结果观察组女性患者比例(47.8%)显著高于对照组(22.8%,P<0.05);观察组与对照组TNM分期Ⅳ期患者比例分别为71.5%和63.3%,差别有统计学意义(P<0.05);观察组腺癌比例(69.9%)显著高于对照组(51.1%,P<0.05);观察组半年、1年及2年生存率分别为71.0%、61.3%和44.6%,对照组为70.6%、60.6%和43.3%,差别无统计学意义(P>0.05)。结论青年肺癌病理分型以腺癌常见,女性及TNM分期Ⅳ期患者比例高于老年患者,年龄与患者生存率未见显著相关。
Objective To investigate the clinical characteristics and prognosis of 186 young patients with lung cancer. Methods A total of 186 young patients with lung cancer who were admitted to our hospital from February 2001 to February 2011 were selected as the observation group and 180 elderly patients with lung cancer who were hospitalized in the same period were selected as the control group. Six months, one year and two years survival and clinical characteristics of the two groups were compared. Results The proportion of female patients in observation group (47.8%) was significantly higher than that in control group (22.8%, P <0.05). The proportion of TNM stage Ⅳ patients in observation group and control group was 71.5% and 63.3% respectively, with significant difference <0.05). The proportion of adenocarcinoma in observation group (69.9%) was significantly higher than that in control group (51.1%, P <0.05). The 6-year, 1-year and 2-year survival rates were 71.0%, 61.3% and 44.6% Group was 70.6%, 60.6% and 43.3%, the difference was not statistically significant (P> 0.05). Conclusion The pathological type of lung cancer in young patients with adenocarcinoma is common. The proportion of female and TNM stage Ⅳ patients is higher than that of elderly patients. There is no significant correlation between age and patient survival rate.