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病历:华人男性患儿,9岁于1975年10月因一年来发热、苍白、体重减轻、面部、颈部及腹部肿胀而就诊。患儿瘦弱、发烧、全身淋巴结肿大、腹水、肝大肋下5 cm、脾大肋下7 cm、血色素3.6gm%、白细胞8800/mm~3、血小板20000/mm~3、血清白蛋白与球蛋白比值为2.9/3.3、胆红质1.7 mg%、硷磷酶156单位。胸部X线见纵隔淋巴结增大兼稍许肺浸润。骨髓正常。淋巴结活检确诊为何杰金氏病,淋巴细胞减消型、临床定为Ⅳ期B。经正规MOPP方案化疗,四个月后肿大淋巴结完全消失,肝缩小到肋下3 cm,脾为肋下4 cm。经6轮化疗后本打算每3个月给一轮维持治疗,但因肝脾未继续缩小而见颈部腋下有淋巴结肿大而改
Medical records: Chinese male child, 9 years old in October 1975 due to one year fever, pale, weight loss, facial, neck and abdomen swelling treatment. Children with emaciation, fever, generalized lymphadenopathy, ascites, hepatomegaly 5 cm, splenic big rib 7 cm, hemoglobin 3.6gm%, white blood cells 8800 / mm ~ 3, platelets 20000 / mm ~ 3, The globulin ratio was 2.9 / 3.3, the bilirubin 1.7 mg%, and the alkaline phosphatase 156 units. See the chest X-ray mediastinal lymph nodes and slightly increased lung infiltration. Normal bone marrow. Lymph node biopsy diagnosed as Hodgkin’s disease, lymphocyte abrogation type, clinical stage IV. After formal MOPP regimen chemotherapy, swollen lymph nodes completely disappeared after four months, the liver reduced to 3 cm under the ribs, the spleen to the ribs 4 cm. After six rounds of chemotherapy, intends to give a round of maintenance treatment every three months, but because of the liver and spleen did not continue to shrink and see the neck armpit lymph nodes and change