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目的探讨妊娠中晚期体重增长速度与孕期总增重和新生儿出生体重的关系。方法回顾性分析2011年8月至2012年2月在北京妇产医院进行常规产前检查和分娩的孕妇临床资料,记录年龄、分娩孕周、身高、孕前体重、分娩前体重、孕期体重监测数据、新生儿出生体重、性别等资料。对资料进行t检验、单因素方差分析、Spearman相关性分析和多元线性回归分析。结果孕妇妊娠中期增重速度[(0.68±0.26)kg/周]大于妊娠晚期增重速度[(0.52±0.25)kg/周],差异有统计学意义(P<0.01)。妊娠中期增重速度与孕期总增重(r=0.446,P<0.01)、新生儿出生体重(r=0.123,P<0.01)皆呈正相关;而妊娠晚期增重速度只与孕期总增重呈正相关(r=0.560,P<0.01),与新生儿出生体重则无显著相关性(r=-0.025,P>0.05);巨大儿组和正常体重儿组孕妇的孕前BMI[(22.3±2.9)kg/m~2 vs.(20.8±2.8)kg/m~2]、孕期总增重[(18.5±4.3)kg vs.(16.6±4.6)kg]和妊娠中期增重速度[(0.74±0.26)kg/周vs.(0.67±0.26)kg/周]相比,巨大儿组皆高于正常体重儿组,P值均<0.01;而2组的妊娠晚期增重则无明显差异(P>0.05)。结论不同孕期体重增长速度对新生儿出生体重的影响可能不同,妊娠中期增重速度对新生儿出生体重的影响大于妊娠晚期增重速度。
Objective To explore the relationship between the rate of weight gain during the second trimester of pregnancy and the total weight gain during pregnancy and the birth weight of newborns. Methods The clinical data of pregnant women who underwent routine prenatal examinations and deliveries at Beijing Maternity Hospital from August 2011 to February 2012 were retrospectively analyzed. The age, birth gestational age, height, weight before pregnancy, body weight before delivery, body weight monitoring data during pregnancy , Birth weight, gender and other information. Data were analyzed by t-test, one-way ANOVA, Spearman correlation analysis and multivariate linear regression analysis. Results The rate of weight gain in the second trimester of pregnant women [(0.68 ± 0.26) kg / week] was significantly higher than that in the third trimester of pregnancy [(0.52 ± 0.25) kg / week], the difference was statistically significant (P <0.01). The rate of weight gain during the second trimester was positively correlated with the total weight gain during pregnancy (r = 0.446, P <0.01) and the newborn birth weight (r = 0.123, P <0.01) (R = -0.025, P> 0.05). The pre-pregnancy BMI of pregnant women in macrosomia group and normal weight group [(22.3 ± 2.9) kg / m ~ 2 vs. (20.8 ± 2.8) kg / m ~ 2], total weight gain during pregnancy [(18.5 ± 4.3) kg vs. (16.6 ± 4.6) kg] and weight gain during the second trimester [(0.74 ± 0.26 (P <0.01). However, there was no significant difference between the two groups in the third trimester of pregnancy (P> 0.05). Conclusion The effects of weight gain during different pregnancy stages on newborn birth weight may be different. The effect of weight gain during mid pregnancy on newborn birth weight is greater than that of late pregnancy.