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肌酐(creatine)是人体代谢的一种内源性产物,在肌肉中形成后扩散入血,从尿中排出,其生成量非常恒定,不受食物中蛋白质、尿量的影响。在地方性甲状腺肿,地方性氟中毒等一些医学研究中经常涉及到尿肌酐水平问题。成人24小时尿肌酐的研究及应用在国内外已有报导,但对于7—14岁青少年24小时尿肌酐水平未见详尽论述。为此,我们对河南省济源县(山区)、宝丰县(丘陵)、驻马店市(平原)农村的7—14岁中小学生1500余例24小时尿肌酐进行了测定分析。结果如下:
Creatine is an endogenous product of the body’s metabolism, which diffuses into the blood after it is formed in the muscle and excreted from the urine. The amount of creatine produced is very constant, independent of the amount of protein and urine in the food. In some endemic goiter, endemic fluorosis and other medical research often involves the issue of urinary creatinine levels. 24-hour adult urinary creatinine research and application have been reported at home and abroad, but for 14-year-old adolescents 24-hour urinary creatinine levels are not discussed in detail. To this end, we measured and analyzed more than 1,500 cases of 24-hour urine creatinine in 7-14-year primary and secondary school students in Jiyuan County, Baofeng County (hills) and Zhumadian (Plain) of Henan Province. The result is as follows: