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目的:探讨糖化血红蛋白监测在空腹血糖正常妊娠糖尿病孕妇中的应用价值。方法:选取我院进行产检的孕妇120例,其中正常孕妇和妊娠糖尿病孕妇各60例,分别为对照组和观察组。观察两组孕妇的空腹血糖含量(FPG)、糖化血红蛋白含量(HbA1c)及糖化血红蛋白(HbA1c)的阳性率。结果:观察组的FPG和HbA1c含量均明显高于对照组,且HbA1c阳性率也显著高于对照组,两组比较,差异均具有统计学意义(P<0.05)。结论:HbA1c检测方法快速,流程简单,特异性较高,稳定性好,受外界因素影响较少,可作为临床上筛查、诊断和检测GDM的生化指标。
Objective: To investigate the value of glycosylated hemoglobin (HbA1c) monitoring in pregnant women with normal fasting plasma glucose (GFP). Methods: 120 pregnant women in our hospital for childbirth were selected, including 60 normal pregnant women and 60 pregnant women with gestational diabetes mellitus, which were control group and observation group respectively. The positive rate of fasting blood glucose (FPG), HbA1c and HbA1c in two groups of pregnant women were observed. Results: The contents of FPG and HbA1c in the observation group were significantly higher than those in the control group, and the positive rate of HbA1c in the observation group was also significantly higher than that in the control group. There was significant difference between the two groups (P <0.05). Conclusion: The method of HbA1c detection is rapid, the process is simple, the specificity is high, the stability is good, and it is less affected by external factors. It can be used as a biochemical index for clinical screening, diagnosis and detection of GDM.