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目的探讨斯氏屋顶鼠对抗凝血灭鼠剂的抗药性变化。方法参照全国鼠类抗药性监测协作组统一方法,进行无选择性摄毒试验。结果经对广州市所辖9个区内所捕获的53只斯氏屋顶鼠进行抗药性监测,存活率为3.8%,其总平均摄药剂量为30.31mg/kg,存活平均摄药剂量为58.29mg/kg。经与同期同地家栖鼠抗药性比较,该鼠种对第一代抗凝血灭鼠剂敏感性介于黄胸鼠与褐家鼠之间。结论控制斯氏屋顶鼠可使用第一代抗凝血灭鼠剂,但应加强对灭鼠药物的敏感性监测,科学、合理用药。
Objective To investigate the resistance changes of Smith’s roof rat to anticoagulant rodenticides. Methods With reference to the unified method of collaborative monitoring of drug resistance in rats in China, selective non-selective test was conducted. Results Fifty-three S. szechenyi rats captured in 9 districts of Guangzhou were tested for drug resistance with a mean survival rate of 3.8%. The total average dose was 30.31 mg / kg and the average survival dose was 58.29 mg / kg. Compared with the homeostasis resistance of the same period in the same period, the sensitivity of the mouse species to the first generation of anticoagulant rodenticides was between that of the rodenticatus and the rodent. Conclusion The first generation of anticoagulant rodenticides can be used to control S. sousheris, however, the sensitivity of rodenticides should be monitored, scientifically and rationally.