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目的:观察为手足口病患儿应用炎琥宁与干扰素联合治疗的临床效果。方法:选取2012年06月~2013年06月我院收治的手足口病患儿100例,按随机数字表法将其分成实验组50例,对照组50例,应用炎琥宁与干扰素联合治疗实验组患儿,应用利巴韦林治疗对照组患儿,比较两组临床治疗效果。结果:与对照组相比,实验组手足口病患儿的治疗效果更佳。实验组患儿口腔溃疡消退时间、手足皮疹消退时间、退热时间、总病程分别为(3.02±1.12)d、(2.29±0.32)d、(1.56±1.20)d、(4.08±0.48)d,均短于对照组,此外,实验组患儿临床治疗有效率为96.0%,显著高于对照组的80.0%,组间差异具有统计意义(P<0.05)。结论:炎琥宁与干扰素联合治疗小儿手足口病,临床效果显著,值得进一步应用。
Objective: To observe the clinical effect of combined treatment of Yanhu Ning and interferon for children with hand-foot-mouth disease. Methods: 100 children with hand-foot-mouth disease admitted in our hospital from June 2012 to June 2013 were divided into experimental group (50 cases) and control group (50 cases) according to the random number table method. Yan-Ning combined with interferon Treatment of experimental group of children, the application of ribavirin treatment of children in the control group, the clinical efficacy of the two groups were compared. Results: Compared with the control group, the experimental group treated children with hand-foot-mouth disease better. In the experimental group, the oral ulcer subsided time, hand-foot rash subsided time, the antipyretic time and the total duration of the disease were (3.02 ± 1.12) days, (2.29 ± 0.32 days), (1.56 ± 1.20 days) and (4.08 ± 0.48 days) In the experimental group, the effective rate of clinical treatment was 96.0%, which was significantly higher than that of the control group (80.0%). The difference between the two groups was statistically significant (P <0.05). Conclusion: Yan Hu Ning combined with interferon in the treatment of hand-foot-mouth disease in children, the clinical effect is significant, it is worth further application.