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[目的]观察清肝降脂汤联合西药治疗脂肪肝疗效。[方法]使用随机平行对照方法,将96例门诊患者按就诊顺序号方法简单随机分两组。对照组46例非诺贝特0.1g,3次/d;血脂康胶囊2粒/次,2次/d;烟酸肌醇脂0.5g,3次/d;生活方式调节,控制饮食、增强运动、减轻体重、忌烟限酒等。治疗组46例清肝降脂汤(柴胡10g,白芍15g,茵陈、金钱草、浙贝母、鸡内金、云茯苓、枳实、郁金、莱菔子、醋香附各10g,丹参15g,生黄芪30g,生山楂、荷叶、陈皮各10g;胁痛着加玄胡、川楝子;中焦湿热伴转氨酶升高者加薏米气滞加木香),1剂/d,水煎300m L,早晚口服;西药治疗同对照组。连续治疗3个月为1疗程。观测临床症状、甘油三酯、总胆固醇、β-脂蛋白、不良反应。连续治疗2疗程,判定疗效。[结果]治疗组治愈32例,有效15例,无效1例,总有效率97.92%。对照组治愈22例,有效14例,无效12例,总有效率73.00%。治疗组疗效优于对照组(P<0.05)。[结论]清肝降脂汤联合西药治疗脂肪肝,疗效满意,无严重不良反应,值得推广。
[Objective] To observe the therapeutic effect of Qinggan Jiangzhi Decoction combined with western medicine on fatty liver. [Methods] Using randomized parallel control method, 96 outpatients were randomly divided into two groups according to the sequence number of visiting doctor. Control group, 46 cases of fenofibrate 0.1g, 3 times / d; Xuezhikang capsule 2 capsules / times, 2 times / d; nicotinic acid inositol 0.5g, 3 times / d; lifestyle regulation, diet control, enhanced Exercise, weight loss, alcohol limit wine and so on. Treatment group, 46 cases of Qinggan Jiangzhi Decoction (Bupleurum 10g, white peony root 15g, capillaris, Lysimachiae Fritillaria, chickweed gold, tuckahoe, citrus aurantium, turmeric, Danshen 15g, raw Astragalus 30g, raw hawthorn, lotus leaf, dried tangerine peel 10g; hypochondriac pain plus plus Hu, Toosendan; Fog and fever with transaminase increased plus barley qi stagnation plus wood), 1 / d, Decoction 300m L, morning and evening oral; western medicine treatment with the control group. Continuous treatment of 3 months for a course of treatment. Clinical symptoms were observed, triglycerides, total cholesterol, β-lipoprotein, adverse reactions. Continuous treatment of 2 courses to determine the efficacy. [Results] 32 cases were cured, 15 cases were effective, 1 case was ineffective, and the total effective rate was 97.92%. Control group, 22 cases were cured, effective in 14 cases, 12 cases were ineffective, the total effective rate was 73.00%. The treatment group was better than the control group (P <0.05). [Conclusion] Qinggan Jiangzhi Decoction combined with Western medicine in the treatment of fatty liver has satisfactory curative effect and no serious adverse reactions, which deserves promotion.