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目的:分别考察罗格列酮马来酸盐在大鼠各肠段:空肠、回肠、结肠 的吸收动力学特征及不同的药物浓度和pH值的影响。方法:应用大鼠在体肠吸收实验方法。结果:罗格列酮马来酸盐在空肠、回肠、结肠的吸收速率常数分别为0.0468,0.0766,0.1045h^-1;不同的药物浓度:20,30,45μg·mL^-1在回肠的吸收速率常数分别为0.0766,0.0714,0.0782h^-1,不同的pH值:7.4,7.1,6,8,6,5时在回肠的吸收速率常数分别为0.0766,0.0798,0.0868,0.08