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目的探讨七氟烷联合瑞芬太尼在小儿短小手术麻醉中的应用价值。方法选取2015年1-6月沈阳二四二医院收治的行短小手术的84例患儿为研究对象,按随机数字表法将其分为观察组与对照组,各42例。观察组患儿采用七氟烷复合瑞芬太尼麻醉,对照组患儿单用七氟烷麻醉,比较两组患儿麻醉诱导前(T1)、麻醉诱导时(T2)、切皮时(T3)、手术5 mim后(T4)、手术结束时(T5)的平均动脉压(MAP)、心率(HR)变化情况、拔管时间、苏醒时间及不良反应发生情况。结果 T3、T4、T5时点,观察组患者的MAP、HR均明显低于对照组,差异均有统计学意义(均P<0.05);观察组患儿的拔管时间、苏醒时间均明显短于对照组,差异均有统计学意义(均P<0.05);观察组患儿的不良反应发生率明显低于对照组,差异有统计学意义(P<0.05)。结论七氟烷联合瑞芬太尼在小儿短小手术麻醉中应用效果显著,可稳定患儿血流动力学,麻醉迅速且恢复时间短,安全性高。
Objective To investigate the value of sevoflurane combined with remifentanil in short-term anesthesia in children. Methods Eighty-four children underwent short-term surgery admitted from January to June 2015 in Shenyang Hospital from January to June 2015 were selected as the research object, and divided into observation group and control group according to random number table method, with 42 cases in each group. The children in the observation group were anesthetized with sevoflurane and remifentanil. The children in the control group were anesthetized with sevoflurane alone. Before treatment (T1), when induction of anesthesia (T2) ), Mean arterial pressure (MAP), heart rate (HR), extubation time, recovery time and adverse reactions after 5 mim of operation (T4) and at the end of operation (T5). Results At the time points of T3, T4 and T5, MAP and HR in the observation group were significantly lower than those in the control group (all P <0.05). The extubation time and recovery time in the observation group were significantly shorter There were significant differences in the control group (all P <0.05). The incidence of adverse reactions in the observation group was significantly lower than that in the control group (P <0.05). Conclusion Sevoflurane combined with remifentanil has a significant effect in short-term anesthesia in pediatric patients, which can stabilize the hemodynamics of children, prompt anesthesia, short recovery time and high safety.