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冠状动脉粥样硬化性心脏病又称冠心病(CHD),是由于冠状动脉粥样斑块形成、冠状动脉痉挛造成冠状动脉狭窄或完全堵塞,从而导致心肌缺血、缺氧,诱发心绞痛或者心肌梗死。大量的临床及基础实验已经证实血脂异常是诱发冠心病的主要因素,近年来得益于他汀类药物的广泛使用,冠心病患者的LDL-C水平有了显著改善,使心血管事件发生率降低了25%~45%~([1-3])。但是在将
Coronary atherosclerotic heart disease, also known as coronary heart disease (CHD), is caused by the formation of coronary atherosclerotic plaques and coronary artery stenosis or complete blockage of coronary artery spasm resulting in myocardial ischemia, hypoxia, angina pectoris or myocardium Infarct. A large number of clinical and basic experiments have confirmed that dyslipidemia is the main factor inducing coronary heart disease, in recent years thanks to the widespread use of statins, coronary heart disease patients with LDL-C levels have been significantly improved, reducing the incidence of cardiovascular events 25% ~ 45% ~ ([1-3]). But will be