保泰松的毒性反应较多见,本文报告一例大剂量急性中毒导致肝、肾及胃肠道同时损害,简介如下。患者(住院号46293),男,75岁,诉服大剂量保泰松后,发生无尿,精神恍惚36小时,于1965年10月14日入院。忠者4年前手、足各小关节反复红肿疼痛,逐渐加剧。2年前出现手足小关节畸型。曾在它院诊断为风湿样关节炎。自1964年2月开始断续服用保泰松600毫克/日,累积总量已达70余克。入院前36小时因关节疼痛加剧,4小时内分次服用保泰松117片(每片100毫克)。服后关节疼痛缓解。但感无力、口 Phenylbutazone toxicity is more common, this report reports a case of high-dose acute poisoning led to liver, kidney and gastrointestinal damage at the same time, are as follows. The patient (hospital number 46293), male, 75 years old, was admitted to hospital on October 14, 1965, following an anuria, trance 36 hours after taking a large dose of phenylbutazone. 4 years ago loyal hand, foot swelling and pain repeatedly small joints, and gradually aggravated. 2 years ago hand, foot and facet joint deformity. Had diagnosed rheumatoid arthritis in her hospital. Since February 1964 intermittent use of phenylbutazone 600 mg / day, the cumulative total has reached more than 70 grams. Thirty-six hours before admission due to increased pain in joints, 4 doses of Phenylbutazone 117 tablets (100 mg each). After the joint pain relief. But feeling weak, mouth