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目的制备一种以鱼腥草为主要原料治疗烧、烫伤的喷膜药剂,并对其治疗功效进行研究。方法采用80%乙醇对鱼腥草、虎杖、大黄、金银花进行回流萃取,辅以冰片,聚乙烯吡咯烷酮制成鱼腥草烫伤喷膜剂,通过对小鼠烫伤模型的作用与森源烧烫伤软膏进行比较评价其治疗功效,并对其安全性及稳定性进行测定。结果鱼腥草烫伤喷膜剂无急性毒性和过敏性,具有较好的稳定性,对试验性烫伤的治疗作用明显。结论该工艺制备的鱼腥草烫伤喷膜剂具有制备简单、易于使用、稳定性好的特点,同时对烫伤具有较好的治疗效果。
Objective To prepare a kind of spray medicine which takes Houttuynia Cordata as main raw material to treat burn and scald and study its curative effect. Methods Houttuynia, Polygonum cuspidatum, Rhubarb, Honeysuckle were extracted with 80% ethanol, and then made into ice cream by injection of borneol and polyvinylpyrrolidone. To compare the evaluation of the efficacy of its treatment, and its safety and stability were determined. Results Houttuynng scald spray without acute toxicity and allergic, with good stability, the treatment of experimental scalds obvious. Conclusion The preparation of Houttuynia scald spray with simple preparation, easy to use, good stability characteristics, while the scald has a good therapeutic effect.