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自从抗菌素问世以来,对感染性疾病发挥了巨大的作用。但在治疗中发现这类药物通过一般方法对某些器官(眼、耳等)或局部病变效果不够理想。如肌肉注射、外敷滴眼、滴耳等进入患病组织的药量太少。大量或长期用药常有副作用。局部抗菌素浸润则组织内张力增加,影晌血运及组织的生命力。20多年以前国外即有人注意采用直流电药物离子透入的方法来弥补上述缺点,如Von Sallmann(1944)首先报告青霉素电透入(Electrophoresis)治疗眼科疾病,并在动物实验中抽取前房液证明电透入的药
Since the advent of antibiotics, infectious diseases have played a huge role. However, in the treatment of such drugs found by some of the general methods of organs (eyes, ears, etc.) or local lesion less than ideal. Such as intramuscular injection, topical drops, drops of ear into the diseased tissue dose too little. A lot of or long-term medication often side effects. Local antibiotic infiltration increases the tension within the tissue, affecting blood flow and tissue vitality. More than 20 years ago, people abroad paid attention to the use of direct current drug iontophoresis to remedy these shortcomings. For example, Von Sallmann (1944) first reported penicillin electrophoresis for the treatment of ophthalmological diseases, Penetrating medicine