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目的:对比研究丙型肝炎患者的胶体金法与酶联免疫法检验结果.方法:回顾性选取2020年2月-2021年2月本院检验科丙型肝炎患者100例,依据检测方法分为胶体金法组、酶联免疫法组两组,各50例,统计分析两组检测结果、检测时间、检测成本.结果:胶体金法组的敏感度为100.00％(44/44),特异度为50.00％(3/6),准确度为94.00％(47/50),阳性预测值为93.62％(44/47),阴性预测值为100.00％(3/3).酶联免疫法组的敏感度为97.73％(43/44),特异度为16.67％(1“,”Objective: To compare the results of colloidal gold method and enzyme - linked immunosorbent assay in patients with hepatitis C. Methods: 100 cases of patients with hepatitis C in the laboratory department of our hospital from February 2020 to February 2021 were retrospectively selected. According to the detection methods, they were divided into coHoidal gold method group and enzyme - linked immunosorbent assay group, with 50 cases in each group. The detection results, detection time and detection costs of the two groups were statistically analyzed. Results:In the coHoidal gold method group, the sensitivity was 100. 00％ (44 / 44), the specificity was 50. 00％ (3 -/ 6), the accuracy was 94. 00％ (47 / 50), the positive predictive value was 93. 62％ (44 / 47 ), and the negative predictive value was 100. 00％ ( 3 / 3 ). In the enzyme -linked immunosorbent assay group, the sensitivity was 97. 73％ (43 / 44), the specificity was 16. 67％ ( 1 / 6), the accuracy was 88. 00％ (44 / 50), the positive predictive value was 89. 58％ (43 / 48), and the negative predictive value was 50. 00％ ( 1 / 2). The sensitivity, specificity,accuracy, positive predictive value and negative predictive value of the coHoidal gold method group were higher than those of the enzyme -linked immunosorbent assay group ( P ＜ 0. 05 ). The detection time of the coHoidal gold method group was shorter than that of the enzyme - linked immunosorbent assay group ( P ＜ 0. 05 ), and the detection cost was higher than that of the enzyme - linked immunosorbent assay group ( P ＜0. 05 ). Conclusion: The results of coHoidal gold method in patients with hepatitis C are better than those of enzyme - linked immunosorbent assay, so is worthy of promotion and application in the clinical.