血清总溶血补体(CH50)活性或补体3(C3)浓度的减少。或二者都减少是急性肾小球肾炎,系膜毛细血管性肾小球肾炎和系统性红斑狼疮的一个标志。而其他类型肾炎,除少数外,大多数患者血清补体是正常的。但少数人血清补体是升高的。1972年Gabriel等注意到:CH50活性升高的患者,其肾功能急剧恶化,但还没有研究报告去证实或否定这一发现。 Serum total hemolytic complement (CH50) activity or reduction in complement 3 (C3) concentration. Or both, is a hallmark of acute glomerulonephritis, mesangial capillary glomerulonephritis, and systemic lupus erythematosus. Other types of nephritis, except for a few, have a normal serum complement in most patients. However, a small number of human serum complement is elevated. In 1972, Gabriel et al noted that in patients with elevated CH50 activity, their renal function deteriorated rapidly, but no study has yet been reported to confirm or deny the finding.