论文部分内容阅读
目的:观察炎琥宁注射液佐治小儿手足口病的临床疗效。方法:将99例手足口病患儿随机分为两组,治疗组50例,对照组49例。两组均给予维生素B、维生素C静脉滴注及对症治疗和利巴韦林10～15 mg/(kg.d)静脉滴注,每天1次,合并细菌感染者给予抗生素治疗,治疗组在此基础上加用炎琥宁注射液6 mg/(kg.d)静脉滴注,每天1次,疗程5～7 d。结果:治疗组总有效率94.00%,对照组总有效率75.51%,两组比较差异有统计学意义(P<0.01);治疗组退热时间、口腔溃疡愈合时间及住院时间均短于对照组,两组比较差异均有统计学意义(P<0.05),两组皮疹消退时间比较差异有统计学意义(P<0.01)。结论:炎琥宁注射液辅助治疗小儿手足口病疗效确切,见效快,疗程短,未见明显不良反应,值得临床推广。
Objective: To observe the clinical efficacy of YanHuNing injection in treating infantile HFMD in children. Methods: Ninety-nine children with HFMD were randomly divided into two groups: treatment group (50 cases) and control group (49 cases). Both groups were given vitamin B, vitamin C intravenous infusion and symptomatic treatment and ribavirin 10 ~ 15 mg / (kg.d) intravenous infusion, once a day, patients with bacterial infection were given antibiotics, the treatment group in this Based on the use of Yan Huaning injection 6 mg / (kg.d) intravenous infusion, 1 day, treatment of 5 ~ 7 d. Results: The total effective rate was 94.00% in the treatment group and 75.51% in the control group, with significant difference between the two groups (P <0.01). The antipyretic time, healing time of oral ulcer and hospital stay in the treatment group were shorter than those in the control group (P <0.05). There was significant difference between two groups in the regression time of rash (P <0.01). Conclusion: Yan Hu Ning injection adjuvant treatment of children with hand foot and mouth disease is effective, quick, short course of treatment, no obvious adverse reactions, is worth clinical promotion.