论文部分内容阅读
目的 :观察胃癌患者血清一氧化氮 ( NO)含量变化及其与肿瘤恶性程度的关系。方法 :采用改进 Griess法测定 2 8例胃癌患者血清 NO含量 ,并探讨其与胃癌病理分级、淋巴结转移的关系。结果 :胃癌患者血清 NO含量明显高于对照组 ( P<0 .0 1 ) ;病理分级中 , 、 级组血清 NO含量显著高于 、 级组 ( P<0 .0 1 ) ;淋巴结转移组血清 NO含量显著高于无淋巴结转移组 ( P<0 .0 5)。结论 :胃癌患者血清 NO含量变化与肿瘤的病理分级和转移等生物学行为密切相关 ,测定血清 NO含量对胃癌的诊断和预后可能具有价值
Objective: To observe the change of serum nitric oxide (NO) and its relationship with malignancy of gastric cancer. Methods: The serum Gris method was used to detect serum NO levels in 28 patients with gastric cancer, and its relationship with pathological grade and lymph node metastasis was discussed. Results: The serum NO content in gastric cancer patients was significantly higher than that in the control group (P<0.01). In the pathological grade, the serum NO levels in the and grade group were significantly higher than those in the grade group (P<0.01); The content of NO was significantly higher than that of the group without lymph node metastasis (P<0.05). Conclusion : The change of NO in serum of patients with gastric cancer is closely related to the biological behavior such as pathological grade and metastasis of tumor. The determination of serum NO may have value in the diagnosis and prognosis of gastric cancer.