论文部分内容阅读
[目的]观察柴胡龙骨牡蛎汤联合尼尔雌醇治疗更年期潮热疗效。[方法]使用随机平行对照方法,将100例门诊及住院患者按就诊顺序编号法随机分为两组。对照组50例尼尔雌醇5mg/次,1次/30d;或2mg/次,1次/14d。症状改善后维持量每次1~2mg,2次/30d。治疗组50例柴胡龙骨牡蛎汤(柴胡20g,茯苓9g,大黄后下4g,半夏、人参、黄芩、桂枝、生龙骨、生牡蛎各10g,大枣、炒枣仁各5g)。1剂/d,凉水浸泡1h后煎40min,水煎200mL,早晚口服。西药治疗同对照组。连续治疗30d为1疗程。观测临床症状、不良反应。连续治疗3疗程,判定疗效。[结果]治疗组痊愈50例,有效0例,无效0例,总有效率100%。对照组痊愈22例,有效10例,无效18例,总有效率64.00%。治疗组疗效优于对照组(P<0.01)。[结论]柴胡龙骨牡蛎汤联合尼尔雌醇治疗更年期潮热效果显著,值得推广。
[Objective] To observe the effect of Chaihu Longgu Muli Decoction combined with nilestriol on the treatment of menopausal hot flashes. [Methods] Using randomized parallel control method, 100 cases of outpatients and inpatients were randomly divided into two groups according to the sequence numbering method. The control group of 50 cases of nilestriol 5mg / time, 1 / 30d; or 2mg / time, 1 / 14d. Symptoms to maintain the amount of improvement after each 1 ~ 2mg, 2 times / 30d. The treatment group of 50 cases of Bupleurum Oyster Soup (Bupleurum 20g, Poria 9g, rhubarb 4g, Pinellia, ginseng, skullcap, cassia, raw keel, raw oysters each 10g, jujube, fried Zaoren each 5g). 1 / d, cold water immersion 1h fried 40min, decoction 200mL, sooner or later oral. Western medicine treatment with the control group. Continuous treatment of 30d for a course of treatment. Observed clinical symptoms, adverse reactions. Continuous treatment of 3 courses to determine the efficacy. [Results] The treatment group cured 50 cases, 0 cases, 0 cases, the total effective rate was 100%. In the control group, 22 cases were cured, 10 cases were effective, 18 cases were ineffective, and the total effective rate was 64.00%. The treatment group than the control group (P <0.01). [Conclusion] Chaihu Longgu Muli Decoction combined with nilestriol has significant effect in treating hot climacteric during menopause and is worth promoting.