论文部分内容阅读
目的探讨先天性心脏病孕期相关高危致病因素。方法回顾性分析先天性心脏病胎儿的孕妇及对照组孕妇资料,分析比较年龄、孕产次、孕期感染及用药、胎儿合并染色体异常及心外异常与先心病的相关性。结果 (1)孕妇年龄增大与胎儿先天性心脏病风险增大相关,P<0.05;(2)先天性心脏病胎儿/患儿合并心外畸形及染色体异常几率较无先天性心脏病胎儿/患儿增高;(3)孕期感染及用药与胎儿先天性心脏病发生相关。结论联合超声检查和染色体核型分析对先天性心脏病胎儿的早期诊断起重要作用;加强孕妇孕早期宣教,避免感染及不合理用药有助于减少先天性心脏病的发生。
Objective To investigate the risk factors of pregnancy-related high-risk congenital heart disease. Methods Retrospective analysis of pregnant women and control group of pregnant women with congenital heart disease data, analysis and comparison of age, pregnancy, infection and medication during pregnancy, fetal chromosomal abnormalities and extracardiac abnormalities and congenital heart disease. Results (1) The increasing age of pregnant women was associated with the increased risk of congenital heart disease in fetuses (P <0.05). (2) The risk of congenital heart disease was higher than those without congenital heart disease Children with increased; (3) pregnancy infection and medication associated with fetal congenital heart disease. Conclusions Combined ultrasound examination and karyotype analysis play an important role in the early diagnosis of congenital heart disease fetus. To strengthen pregnant women in early pregnancy to avoid infection and irrational medication may help to reduce the occurrence of congenital heart disease.