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目的了解陕西省千阳县近5年出生缺陷发生情况和变化趋势,分析原因,制定干预措施。方法对2009-2013年在县人民医院和县妇幼保健院住院分娩的7 135例孕13~27周引产的出生缺陷儿和28周至生后7 d的围产儿进行出生缺陷监测,对监测结果进行统计分析。结果千阳县2009-2013年出生缺陷发生率逐年下降,神经管缺陷发生率2009年为96/万,2012年起明显下降,产前诊断确诊率也逐年下降。结论实施增补服叶酸预防出生缺陷项目和孕产妇健康管理项目以来,本地区出生缺陷发生率逐年下降。因此,补服叶酸、加强围产期保健、提高产前诊断等措施,可减少出生缺陷的发生。
Objective To understand the occurrence and trend of birth defects in Qianyang County of Shaanxi Province in recent 5 years, analyze the causes and make interventions. Methods A total of 7 135 newborns with abortion underwent induction of labor during 13 to 27 weeks of gestation and 28 days of gestation and 7 days after birth in 2009 ~ 2013 in County People’s Hospital and County Maternal and Child Health Hospital. The monitoring results were analyzed Statistical Analysis. Results The incidence of birth defects in Qianyang from 2009 to 2013 decreased year by year. The incidence of neural tube defects was 96 per ten thousand in 2009 and decreased significantly from 2012, and the diagnosis rate of prenatal diagnosis also decreased year by year. Conclusions Since the implementation of supplementary folic acid supplementation folic acid to prevent birth defects and maternal health management projects, the incidence of birth defects in the region decreased year by year. Therefore, supplement folic acid, to enhance perinatal care, improve prenatal diagnosis and other measures to reduce the incidence of birth defects.