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妊娠期高血压病(Hypertensive disorder complicating pregnancy,HDCP)是一种妊娠期特有的疾病,其发病机制目前仍不十分明确,其发病过程严重危害母儿健康,是孕产妇及围生儿妊娠不良结局的重要原因,我国发病率约为9.4%[1]。其发病机制可能与异常滋养细胞侵入子宫肌层、血管内皮炎性损伤及免疫炎症反应的过度应答等有关,近年来针对膜联蛋白Ⅰ与妊娠期高血压病的相关性时有报道,本篇就膜联蛋白Ⅰ与妊娠期高血压病的研究概况作一综述。
Hypertensive disorder complicating pregnancy (HDCP) is a peculiar disease of pregnancy. The pathogenesis of HDCP is still not very clear at present. The pathogenesis of HDCP is seriously endangering the health of pregnant women and children. It is the unhealthy outcome of pregnant women and perinatal pregnancies The important reason, the incidence of our country is about 9.4% [1]. The pathogenesis may be related to abnormal trophoblast cells invade the myometrium, endothelium inflammatory injury and immune response to inflammation and other over-related, in recent years for annexin I and gestational hypertension is sometimes reported in this article This review summarizes the research progress of annexin Ⅰ and gestational hypertension.