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目的观察孕37~39周剖宫产前使用地塞米松预防新生儿呼吸窘迫综合征(RDS)的临床疗效。方法选取该院2014年1月-2015年1月收治的孕37~39周行剖宫产的孕妇120例,按随机双盲对照法分为治疗组和对照组各60例。治疗组手术前给予地塞米松,对照组不给予地塞米松。观察2组术后新生儿RDS的发生率。结果治疗组剖宫产新生儿RDS的发生率为1.67%(1/60)明显低于对照组的11.67%(7/60),差异有统计学意义(P<0.05)。结论对孕37~39周剖宫产孕妇术前使用地塞米松能明显降低术后新生儿RDS的发生率,改善新生儿的结局,值得临床推广应用。
Objective To observe the clinical efficacy of dexamethasone for preventing neonatal respiratory distress syndrome (RDS) before cesarean section during 37-39 weeks of gestation. Methods A total of 120 pregnant women undergoing cesarean section at 37-39 weeks of gestation from January 2014 to January 2015 in our hospital were selected and divided into two groups according to randomized double-blind control: 60 cases in each group. Dexamethasone was given to the treatment group before surgery, and dexamethasone was not given to the control group. The incidence of postoperative neonatal RDS was observed. Results The incidence of RDS in neonates with cesarean section in the treatment group was 1.67% (1/60), which was significantly lower than that in the control group (11.67%, 7/60) (P <0.05). Conclusion Preoperative use of dexamethasone in pregnant women with cesarean section at 37-39 weeks of gestation can significantly reduce the incidence of postoperative neonatal RDS and improve the outcome of newborns, which deserves clinical application.