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多种药物可引起口腔干燥症,尤其是长期服用趋精神药可引起明显的口腔干燥症状。本次探讨了人参养荣汤对3种趋精神药引起的唾液分泌抑制的恢复作用,并与白虎加人参汤进行了比较。 方法:实验动物为Wistar系雄性大鼠(体重220g)。为了探讨趋精神药的唾液分泌抑制作用,每日2次,共7d腹腔内给予地西泮(0.05～0.4mg/kg)、氟哌啶醇(0.1～0.5mg/kg)、阿米替林(0.25～0.1mg/kg)。与汉方药并用时,地西泮与
A variety of drugs can cause xerostomia, especially long-term use of psychotropic drugs can cause significant symptoms of dry mouth. This study explored the effect of Ginseng Yangrongtang on the recovery of saliva secretion caused by three psychotropic drugs, and compared it with Baihujia and Ginseng soup. Methods: The experimental animals were Wistar male rats (body weight 220g). In order to investigate the inhibitory effect of psychotropic drugs on saliva secretion, diazepam (0.05-0.4 mg/kg), haloperidol (0.1-0.5 mg/kg), amitriptyline were administered intraperitoneally twice a day for 7 days. (0.25 to 0.1 mg/kg). When combined with Kampo medicine, Diazepam