Wilson—Mikity综合征(简称WMS),是发生在极低体重儿的一种慢性呼吸困难疾病。1960年首次由美国的Wilson和Mikity所报道,后为世界各国公认,并以此命名。本病为一种独立疾病,长期来病因不明,近年来日本有较多的研究并证明与胎儿宫内感染有关。一、发病情况: 有报道在1976～1984年间在543例体重<2000g的低体重儿中有35例患本病,发病率为6.4％,按日本人口动态统计体重<2000g占总出生婴儿的1.2％,故推算本发病率为1/10万。亦有认为本病的发 Wilson-Mikity syndrome (WMS), is a chronic dyspnoea that occurs in very low birth weight infants. It was first reported by Wilson and Mikity in the United States in 1960, later recognized by all the countries in the world and named after it. The disease is an independent disease, the etiology has long been unknown, Japan has more studies in recent years and prove associated with intrauterine infection. First, the incidence: It was reported in 1976 to 1984 in 543 cases of low birth weight children weighing <2000g in 35 cases of the disease, the incidence was 6.4%, according to the Japanese population dynamic body weight <2000g accounted for 1.2% of total newborns %, It is estimated that the incidence of 1/10 million. Also think that this disease hair