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目的观察中西医结合序贯治疗急性早幼粒细胞白血病的疗效、生存期。方法选取急性早幼粒细胞白血病患者60例,随机分成两组,治疗组32例,对照组28例,治疗组应用中西医结合序贯治疗法,对照组应用HA、DA、MA、AA、MD-Ara-C化疗方案序贯治疗,对所有患者定期复查血Rt、骨髓象及融和基因。结果治疗组3年整体生存率93.7%(31/32),5年整体生存率81.3%,对照组3年整体生存率53.5%(15/28),治疗组生存期、生存质量明显优于对照组。结论应用中西医结合序贯治疗急性早幼粒细胞白血病明显优于对照组,明显延长了患者的生存期及CCR率。
Objective To observe the efficacy and survival of sequential treatment of acute promyelocytic leukemia with integrated traditional Chinese and western medicine. Methods Sixty patients with acute promyelocytic leukemia were randomly divided into two groups: treatment group (32 cases) and control group (28 cases). The treatment group received sequential therapy of TCM and WM, and the control group received HA, DA, MA, AA, MD -Ara-C chemotherapy sequential treatment, regular review of all patients blood Rt, bone marrow and thalassemia genes. Results The 3-year overall survival rate was 93.7% (31/32) in the treatment group. The 5-year overall survival rate was 81.3%. The 3-year overall survival rate was 53.5% (15/28) in the control group. The survival and quality of life of the treatment group were significantly better than those of the control group group. Conclusion The sequential treatment of acute promyelocytic leukemia with traditional Chinese and western medicine was significantly better than that of the control group, significantly prolonging the survival rate and CCR rate.