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本文研究铜锌比值不同的饲料对实验性动脉粥样硬化形成和消退的影响。在“形成”实验末和“消退”实验末,低铜锌比饲料组与高铜锌比饲料组相比,血清铜值较小,锌值较大、铜锌比值较小、总胆固醇值较大、高密度脂蛋白胆固醇值较小,动脉粥样硬化程度较重,各项对比均有显著或非常显著差异。“形成”实验末有关数据的相关性检验证实,铜锌比值与总胆固醇值,铜锌比值与总胆固醇/高密度脂蛋白胆固醇比值,总胆固醇值与动脉粥样硬化的斑块计分值,均呈非常显著的相关关系(P<0.01)。本文认为,微量元素铜与锌,特别是铜锌比值,通过影响脂质代谢而影响动脉粥样硬化,低铜锌比饲料加重动脉粥样硬化。
This article studies the effects of different diets with different copper and zinc ratios on the formation and regression of experimental atherosclerosis. At the end of “forming” experiment and “subsided” experiment, the serum copper value was smaller, the zinc value was larger, the ratio of copper and zinc was smaller, the total cholesterol value was lower Large, high-density lipoprotein cholesterol is small, severe atherosclerosis, the contrasts were significant or very significant differences. Correlation testing of the data at the end of “Formed” experiment confirmed that the ratio of copper to zinc to total cholesterol, ratio of copper to zinc to total cholesterol / high density lipoprotein cholesterol, total cholesterol and atherosclerotic plaque score, All showed a very significant correlation (P <0.01). This paper argues that the ratio of trace elements copper and zinc, especially copper and zinc, affects atherosclerosis by affecting lipid metabolism and aggravating atherosclerosis with low copper and zinc diets.