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目的考察奥硝唑氯化钠注射液与氨茶碱、盐酸左氧氟沙星、硫酸阿米卡星注射液配伍的稳定性。方法模拟临床配制配伍液,分别于不同时间观察配伍液的外观,测定其p H值和配伍液中奥硝唑的含量。结果 25℃各配伍液8h内外观没有变化,p H值变化很小,奥硝唑含量均为配伍初时的95%以上。结论奥硝唑氯化钠注射液与氨茶碱、盐酸左氧氟沙星、硫酸阿米卡星注射液在25℃可以配伍应用。
Objective To investigate the stability of compatibility of ornidazole and sodium chloride injection with aminophylline, levofloxacin hydrochloride and amikacin sulfate injection. Methods The clinical preparation of compatibility solution was simulated. The appearance of the compatibility solution was observed at different times. The p H value and the content of ornidazole in the compatibility solution were determined. Results There was no change in the appearance and appearance of the compatibility solution at 25 ℃ for 8 hours, but the p H value changed little. The content of ornidazole was above 95% of the initial compatibility. Conclusion Ornidazole sodium chloride injection and aminophylline, levofloxacin hydrochloride, amikacin sulfate injection at 25 ° C compatibility applications.