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目的 :观察敌鼠钠对大鼠睾丸的毒性作用。方法 :以SD雄性大鼠为试验动物 ,一次性灌胃染毒不同剂量敌鼠钠 ,7d后取睾丸制作石蜡切片 ,观察对大鼠睾丸结构的影响 ;同时对附睾内精子进行活性测试。结果 :①敌鼠钠致使活动精子百分率明显下降 ,特别是 1.2 5和 5 .0mg/kg体重大鼠的活动精子降到 5 0 %以下 ;②敌鼠钠可使大鼠睾丸的曲细精管管壁萎缩、变形 ,生精上皮细胞层和精子层厚度明显变薄 ,精母细胞、精子细胞和精子均有不同程度的损伤。结论 :敌鼠钠对大鼠睾丸有一定的损伤作用
Objective: To observe the toxic effect of sodium triphosphate on rat testes. Methods: Male Sprague-Dawley rats were used as experimental animals. Different doses of sodium sevoflurane were administered intragastrically once a day. Paraffin sections were obtained from testis 7 days later to observe the effect on the structure of testis in rats. At the same time, the activity of sperm in the epididymis was tested. Results: (1) The concentration of active spermatozoa decreased significantly in natriuretic mice, especially in spermatozoa with activities of 1.5 and 5.0 mg / kg body weight below 50% Wall atrophy, deformation, spermatogenic epithelial cells and sperm layer thickness thinning, spermatocytes, sperm cells and sperm have varying degrees of damage. CONCLUSION: Sodium chinatsune has certain damage on rat testes